Most popular email marketing services offer functionality that strikes a recipient from a list once a certain number of emails to a specific recipient ‘bounced’ back as undeliverable. Don’t be overeager to remove a subscriber, though; there are valid reasons why an email cannot be delivered. Consider only removing such a subscriber after four or five “bounces”.
The best time to send an email blast depends a little on the best time you think your recipients would like to receive it. Most business contacts receive an average of 75 emails per day. To make sure they have the time to review (and hopefully, read) your email, try to have your email blast arrive on Tuesday Mornings between 8am and 11am. Mondays (especially after holidays) is typically a day where most contacts are catching up on email from the weekend. Fridays are difficult, as most contacts are wrapping up work from the week and may not have the time to look at your message. Even if they do find time to read it, they may have forgotten about you, and your message, by the next Monday. If Monday is a holiday, time your email blast to arrive on a Wednesday Morning after the holiday. Mornings are best as most people are planning or finalizing their day in the mornings. This gives them more time to react to your email message that same day. Afternoons and evenings are typically too late in the workday to encourage immediate action.

Most of the article really talks about how to successfully get an email of a person who has already landed on your landing page/podcast page/affiliate/blog etc. but how to get those people there in the first place is a bigger challenge. Also, one of the ways you can include in your list is by offering free tools/widgets. For example, OpenSiteExplorer by Moz is a great example. Evergreen and very useful for the target audience.
Personalization in email marketing is essential because most people want a more relevant experience. Email personalization is not just about using people’s names in an email. It’s also about making sure you send the right emails to the right people at the right time. One essential tool for email personalization is segmentation. You can get an email marketing expert to help you set up segments so you can personalize appropriately. Done right, email personalization results in more clicks and more business.
Use custom campaign URLs. Google provides a tool where you can create your own unique URL for your particular marketing campaigns. You may include parameters such as your medium, source, content, term, and campaign name. As soon as you have a customized link, you may use it in its complete form or shorten it by using a link shortening tool such as bit.ly.
Most people don't think of email as a lead- or contact-generating channel. But because people forward helpful emails to colleagues or friends, it can actually expand your database if you simply make forwarding or sharing email content easy for recipients. Include calls-to-action in your emails that make sharing an obvious choice for recipients, particularly with your most useful assets.
This ties into the second 40 of the 40/40/20 rule – now you’re probably beginning to see why that was listed up front and why it’s universally considered the gold standard when it comes to direct mail marketing guidelines. With other forms of advertisements or marketing, it is perfectly acceptable to only go after impressions – a billboard in a highly-trafficked area or a TV spot that is more of a teaser in nature can sometimes go a long way toward educating the public of your existence, which is the first step in getting them to engage. With direct mailings however, you might as well be printing cash to send out to people if you don’t have a compelling call to action to give people.
Here are a few tips to help businesses avoid sending email campaigns that qualify as “blasts.” In doing so, you’ll also realize other benefits, including fewer people who unsubscribe from your email lists, fewer emails caught in spam filters, delivery rates that improve, and better overall email performance results that dramatically drive up sales.

Couple your sign-up boxes with a clear description of “what’s in it for them.” Let customers know exactly what to expect when signing up, and sell the benefits for being on your email list. This can be as simple as promoting the general advantages of the channel — such as being able to receive information and offers faster and that it’s eco-friendly.
Choose analytics software that works for your organization. While many email marketing applications have built-in analytics, you may consider getting a third party system to help you process the data or statistics on your campaigns. Some software can give you a more comprehensive or visual representation of your analytics, while others may track something that your current content management system does not. The size and scope of your e-blast campaign will dictate which kind of software you require.
An omni-channel approach not only benefits consumers but also benefits business bottom line: Research suggests that customers spend more than double when purchasing through an omni-channel retailer as opposed to a single-channel retailer, and are often more loyal. This could be due to the ease of purchase and the wider availability of products.[24] 
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