What's the difference between them? One-off communications versus prolonged, email-based interactions. For example, email marketing tools are excellent for one-off communications. You can use these tools for the one time you'd like to send someone an automated email response when they join a subscriber list, on their birthday, or when you promote a new product. But marketing automation tools are better suited for prolonged, email-based interactions. For example, you can use marketing automation tools whenever you want to guide someone from a subscriber list to a product purchase. Or you can send thank you emails or send new product promotions—all without having to lift a finger after the workflow is designed.
As we wrote in an earlier post, 7 Email List Hygiene Best Practices for a Fresh & Clean List, it’s far better to let people unsubscribe – to make it really easy for them to unsubscribe – than to keep them on your list. Don’t blast people – force people – into getting your email messages. Email marketing at its best is not mass advertising. It is tailored, persona-driven, relationship-building, inbound marketing.

A campaign is a marketing message that you share through email or ads. In Mailchimp, most users start with a regular email campaign, which is a bulk email sent to many contacts at once. When you create a regular email campaign in Mailchimp, you’ll use a checklist-style Campaign Builder to add recipients, choose your settings, and design your content.
Particular groups of customers can be targeted or even individuals. Offering individual customers special deals on merchandise and/or services on the customer's birthday, for instance, is one example of email marketing personalization. (A restaurant might send an email to customers on their birthday offering 50% off an entree,) Email marketing helps a business develop and maintain a relationship with a customer over time that hopefully results in increased sales and increased customer loyalty. 
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